diff --git a/Lib/test/test_external_inspection.py b/Lib/test/test_external_inspection.py
index 9fff8e8bff91f7a..7c240eca5bb0ebd 100644
--- a/Lib/test/test_external_inspection.py
+++ b/Lib/test/test_external_inspection.py
@@ -36,6 +36,7 @@
 THREAD_STATUS_ON_CPU = 1 << 1
 THREAD_STATUS_UNKNOWN = 1 << 2
 THREAD_STATUS_HAS_EXCEPTION = 1 << 4
+THREAD_STATUS_MAIN_THREAD = 1 << 5
 
 # Maximum number of retry attempts for operations that may fail transiently
 MAX_TRIES = 10
@@ -2596,6 +2597,40 @@ def test_unsupported_platform_error(self):
 
 @requires_remote_subprocess_debugging()
 class TestDetectionOfThreadStatus(RemoteInspectionTestBase):
+    @skip_if_not_supported
+    def test_cpu_status_with_multiple_thread_states(self):
+        import_module("_testinternalcapi")
+        import_module("_hashlib")
+        code = textwrap.dedent("""
+            import _hashlib
+            def active():
+                while True:
+                    _hashlib.pbkdf2_hmac('sha256', b'password', b'salt', 10_000_000)
+            active()
+        """)
+        script = f"""
+            import _testinternalcapi
+            def suspended():
+                sock.sendall(b"ready")
+                _testinternalcapi.exec_interpreter(0, {code!r})
+            suspended()
+        """
+        with self._target_process(script) as (p, sock, _):
+            _wait_for_signal(sock, b"ready")
+            unwinder = RemoteUnwinder(p.pid, all_threads=True, mode=PROFILING_MODE_ALL)
+            for _ in busy_retry(SHORT_TIMEOUT):
+                trace = _get_stack_trace_with_retry(unwinder)
+                active = self._find_thread_with_frame(trace, lambda f: f.funcname == "active")
+                if active is None or not active.status & THREAD_STATUS_ON_CPU:
+                    continue
+                if active.status & THREAD_STATUS_HAS_GIL:
+                    continue
+                suspended = self._find_thread_with_frame(trace, lambda f: f.funcname == "suspended")
+                self.assertIsNotNone(suspended)
+                self.assertEqual(suspended.thread_id, active.thread_id)
+                self.assertEqual(suspended.status, THREAD_STATUS_MAIN_THREAD)
+                break
+
     def _run_thread_status_test(self, mode, check_condition):
         """
         Common pattern for thread status detection tests.
diff --git a/Misc/NEWS.d/next/Library/2026-10-13-18-00-00.gh-issue-159312.Lk3w9a.rst b/Misc/NEWS.d/next/Library/2026-10-13-18-00-00.gh-issue-159312.Lk3w9a.rst
new file mode 100644
index 000000000000000..99e3878035cf08c
--- /dev/null
+++ b/Misc/NEWS.d/next/Library/2026-10-13-18-00-00.gh-issue-159312.Lk3w9a.rst
@@ -0,0 +1,2 @@
+Fix :mod:`profiling.sampling` attributing CPU samples to suspended thread states
+when multiple thread states share the same native thread.
diff --git a/Modules/_remote_debugging/_remote_debugging.h b/Modules/_remote_debugging/_remote_debugging.h
index 79fa4a92e745bd0..e73f07af18cef32 100644
--- a/Modules/_remote_debugging/_remote_debugging.h
+++ b/Modules/_remote_debugging/_remote_debugging.h
@@ -179,6 +179,9 @@ typedef enum _WIN32_THREADSTATE {
 #define THREAD_STATUS_HAS_EXCEPTION       (1 << 4)
 #define THREAD_STATUS_MAIN_THREAD         (1 << 5)
 
+// Internal marker, removed before returning the sample.
+#define THREAD_STATUS_UNBOUND             (1 << 6)
+
 /* Exception cause macro */
 #define set_exception_cause(unwinder, exc_type, message)                              \
     do {                                                                              \
@@ -686,7 +689,7 @@ extern int get_thread_status(RemoteUnwinderObject *unwinder, uint64_t tid, uint6
 extern PyObject* unwind_stack_for_thread(
     RemoteUnwinderObject *unwinder,
     uintptr_t *current_tstate,
-    uintptr_t gil_holder_tstate,
+    int *has_unbound,
     uintptr_t gc_frame,
     uintptr_t main_thread_tstate,
     const RemoteReadPrefetch *prefetch
diff --git a/Modules/_remote_debugging/module.c b/Modules/_remote_debugging/module.c
index 6fa277d1065ed91..c6e0c4c01cb6b85 100644
--- a/Modules/_remote_debugging/module.c
+++ b/Modules/_remote_debugging/module.c
@@ -650,6 +650,66 @@ read_interp_state_and_maybe_thread_frame(
         interp_state_buffer);
 }
 
+static int
+filter_unbound_cpu_samples(PyObject *result, int skip)
+{
+    PyObject *bound = PySet_New(NULL);
+    if (bound == NULL) {
+        return -1;
+    }
+    // An unbound stack may still be doing native work after a callback.
+    // Exclude it only when a bound stack shares its native thread ID.
+    for (Py_ssize_t i = 0; i < PyList_GET_SIZE(result); i++) {
+        PyObject *threads = PyStructSequence_GET_ITEM(PyList_GET_ITEM(result, i), 1);
+        for (Py_ssize_t j = 0; j < PyList_GET_SIZE(threads); j++) {
+            PyObject *thread = PyList_GET_ITEM(threads, j);
+            long status = PyLong_AsLong(PyStructSequence_GET_ITEM(thread, 1));
+            if (!(status & THREAD_STATUS_UNBOUND) &&
+                PyList_GET_SIZE(PyStructSequence_GET_ITEM(thread, 2)) != 0 &&
+                PySet_Add(bound, PyStructSequence_GET_ITEM(thread, 0)) < 0) {
+                goto error;
+            }
+        }
+    }
+    for (Py_ssize_t i = 0; i < PyList_GET_SIZE(result); i++) {
+        PyObject *threads = PyStructSequence_GET_ITEM(PyList_GET_ITEM(result, i), 1);
+        for (Py_ssize_t j = PyList_GET_SIZE(threads); j-- > 0;) {
+            PyObject *thread = PyList_GET_ITEM(threads, j);
+            long status = PyLong_AsLong(PyStructSequence_GET_ITEM(thread, 1));
+            if (!(status & THREAD_STATUS_UNBOUND)) {
+                continue;
+            }
+            status &= ~THREAD_STATUS_UNBOUND;
+            int found = PySet_Contains(bound, PyStructSequence_GET_ITEM(thread, 0));
+            if (found < 0) {
+                goto error;
+            }
+            if (found) {
+                status &= ~THREAD_STATUS_ON_CPU;
+            }
+            if (skip && !(status & THREAD_STATUS_ON_CPU)) {
+                if (PySequence_DelItem(threads, j) < 0) {
+                    goto error;
+                }
+            }
+            else {
+                PyObject *py_status = PyLong_FromLong(status);
+                if (py_status == NULL) {
+                    goto error;
+                }
+                Py_DECREF(PyStructSequence_GET_ITEM(thread, 1));
+                PyStructSequence_SET_ITEM(thread, 1, py_status);
+            }
+        }
+    }
+    Py_DECREF(bound);
+    return 0;
+
+error:
+    Py_DECREF(bound);
+    return -1;
+}
+
 /*[clinic input]
 @critical_section
 _remote_debugging.RemoteUnwinder.get_stack_trace
@@ -715,6 +775,8 @@ _remote_debugging_RemoteUnwinder_get_stack_trace_impl(RemoteUnwinderObject *self
         return NULL;
     }
 
+    int has_unbound = 0;
+
     // Iterate over all interpreters
     uintptr_t current_interpreter = self->interpreter_addr;
     while (current_interpreter != 0) {
@@ -803,7 +865,7 @@ _remote_debugging_RemoteUnwinder_get_stack_trace_impl(RemoteUnwinderObject *self
         while (current_tstate != 0) {
             uintptr_t prev_tstate = current_tstate;
             PyObject* frame_info = unwind_stack_for_thread(self, &current_tstate,
-                                                           gil_holder_tstate,
+                                                           &has_unbound,
                                                            gc_frame,
                                                            main_thread_tstate,
                                                            &prefetch);
@@ -890,6 +952,11 @@ _remote_debugging_RemoteUnwinder_get_stack_trace_impl(RemoteUnwinderObject *self
         }
     }
 
+    if (has_unbound && filter_unbound_cpu_samples(result,
+            self->mode == PROFILING_MODE_CPU && self->skip_non_matching_threads) < 0) {
+        Py_CLEAR(result);
+    }
+
 exit:
     // Invalidate cache entries for threads not seen in this sample.
     // Only do this every 1024 iterations to avoid performance overhead.
diff --git a/Modules/_remote_debugging/threads.c b/Modules/_remote_debugging/threads.c
index 120065022ddc8ee..5249e6da277afe1 100644
--- a/Modules/_remote_debugging/threads.c
+++ b/Modules/_remote_debugging/threads.c
@@ -332,7 +332,7 @@ PyObject*
 unwind_stack_for_thread(
     RemoteUnwinderObject *unwinder,
     uintptr_t *current_tstate,
-    uintptr_t gil_holder_tstate,
+    int *has_unbound,
     uintptr_t gc_frame,
     uintptr_t main_thread_tstate,
     const RemoteReadPrefetch *prefetch
@@ -611,6 +611,13 @@ unwind_stack_for_thread(
         goto error;
     }
 
+    if ((unwinder->mode == PROFILING_MODE_CPU || unwinder->mode == PROFILING_MODE_ALL) &&
+        !GET_MEMBER(_thread_status, ts, unwinder->debug_offsets.thread_state.status).bound_gilstate &&
+        PyList_GET_SIZE(frame_info) != 0) {
+        status_flags |= THREAD_STATUS_UNBOUND;
+        *has_unbound = 1;
+    }
+
     // Always use status_flags
     PyObject *py_status = PyLong_FromLong(status_flags);
     if (py_status == NULL) {